Cylindroma

Most cylindromas present as single papules of the head and neck in middle aged individuals or the elderly. Multiple disfiguring tumors of the scalp have been described and likened to a turban "turban tumor". Multiple tumors can be seen in the setting of CYLD tumor suppressor gene mutations. Characteristic features of a cylindroma include monomorphous appearing basaloid islands, eosinophilic hyaline-like globules, thickened eosinophilic basement membrane surrounding the lobules and a jigsaw puzzle-like pattern of growth. It is not uncommon to encounter tumors showing features of both cylindroma and spiradenoma.